Since 1892, Harvard University, like many distinguished academic institutions, has compiled a hymnal for use in its own worship services. The fourth edition of The Harvard University Hymn Book represents the culmination of a ten-year process of revision and re-creation based on the 1964 third edition. Containing over 370 hymns, over 100 more than its predecessor, the book includes many that have become a regular part of worship at The Memorial Church in the years since the publication of the previous edition.

In addition to many familiar hymns old and new, the fourth edition includes selections that were unique to the previous editions, hymns previously unpublished, and other noteworthy "discoveries" that have not appeared in print for many years.