ABOUT THIS BOOK
In a remarkable synthesis of the research of the last two decades, a leading developmental neuroscientist provides psychologists with a sophisticated introduction to the brain—the system that underpins the functions that they study.
In clear terms, with ample illustrations, Joan Stiles explains the complexities of genetic variation and transcription, and the variable paths of neural development, from embryology through early childhood. She describes early developmental processes from gene expression to physiology to behavior. Sections on clinical correlations show the consequences for later physiological, neurological, or psychological disturbances in neural development.
As Stiles shows, brain development is far more complex and dynamic than is often assumed in debates about nature vs. nurture, nativism vs. cultural learning. Inherited and experienced factors interact constantly in an ever-changing organism. The key question is, what developmental processes give rise to particular structures or mechanisms?
A landmark of synthesis and interdisciplinary illumination, The Fundamentals of Brain Development will enrich discussion of developmental processes and more rigorously define the terms that are central to psychological debates.
This incisive and accessible account of brain development should be of great interest to the serious student of human behavior. Stiles does a superlative job of reviewing a vast literature, and her discussion of nativism, and the nature/nurture problem, is brilliant. I wish The Fundamentals of Brain Development could be a foundational text for all graduate work in developmental psychology.
-- Charles A. Nelson, Professor of Pediatrics, Harvard Medical School
The Fundamentals of Brain Development, as Stiles intended, is a timely survey of developmental neurobiology. Neuronal differentiation, migration, plasticity, sensitive periods, intrinsic factors and a discussion of experiential environments are all here. It is detailed, beautifully illustrated, thoroughly researched and should become a standard for any researcher who needs to look to neurobiological explanations to account for early developmental changes.
-- Bruce M. Hood Nature
[Stiles] ends up taking readers through a surprisingly detailed exposition of brain development and constructing a scholarly synthesis that will inform not only developmental psychology but even all of neuroscience and cognitive science.
-- Mriganka Sur Science
[Stiles] successfully blends the genetic regulation of brain development with the influence of environment at each developmental stage.
-- L. A. Meserve Choice
TABLE OF CONTENTS
1 The Central Questions about Psychological and Biological Development
2 The Gene: Evolution of a Concept
3 Initial Patterning of the Embryonic Brain: Formation of the Neural Plate
4 Initial Patterning of the Embryonic Brain: Formation of the Neural Tube
5 Molecular Patterning of the Primary Spatial Dimensions of the Embryo
6 The Production of Brain Cells: Neurons and Glia
7 Neuronal Migration and Neuronal Differentiation
8 Shaping the Emerging Cortical Network: The Role of Intrinsic and Extrinsic Factors
9 Late Prenatal and Postnatal Changes in Human Brain Structure
10 Plasticity and the Role of Experience in Neocortical Development
11 The Importance of Brain Development for Psychology